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Bomedemstat is an orally active LSD1 inhibitor that in mouse models ameliorated the hallmarks of MPNs and improved survival Kleppe et al 2015 Jutzi et al 2018 Aims IMG 7289 CTP 102 is an ongoing global open label Phase 2 study evaluating bomedemstat dosed QD in MF patients NCT03136185

IMG 7289 CTP 201 is a global open label Phase 2b study of bomedemstat taken once daily for 24 weeks in patients with ET who are resistant to or intolerant of at least one SOC treatment NCT04254978

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IMG 7289 Ferreting Out The Fun

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Bomedemstat IMG 7289 an LSD1 Inhibitor Manages the Signs and Symptoms of Essential Thrombocythemia ET While Reducing the Burden of Cells Homozygous for Driver Mutations ScienceDirect Volume 142 Supplement 1 2 November 2023 Page 747 Oral Abstracts 634 Myeloproliferative Syndromes Clinical and

A Phase 2 Study of the LSD1 Inhibitor Img 7289 bomedemstat for the Treatment of Advanced Myelofibrosis ScienceDirect PDF Blood Volume 138 Supplement 1 23 November 2021 Page 139 634 Myeloproliferative Syndromes Clinical and Epidemiological

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Bomedemstat IMG 7289 is an orally active and irreversible lysine specific demethylase 1 LSD1 inhibitor Bomedemstat can increase H3K4 and H3K9 methylation and then alter gene expression Bomedemstat shows anti cancer activities inhibits cancer cell proliferation and induces apoptosis

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A Phase 2 Study Of The LSD1 Inhibitor Img 7289 bomedemstat

https://ashpublications.org/blood/article/138...
IMG 7289 CTP 201 is a global open label Phase 2b study of bomedemstat taken once daily for 24 weeks in patients with ET who are resistant to or intolerant of at least one SOC treatment NCT04254978

 IMG 7289 Ferreting Out The Fun
Bomedemstat IMG 7289 An LSD1 Inhibitor Manages The Signs

https://ashpublications.org/blood/article/142...
Bomedemstat IMG 7289 an LSD1 Inhibitor Manages the Signs and Symptoms of Essential Thrombocythemia ET While Reducing the Burden of Cells Homozygous for Driver Mutations

IMG 7289 CTP 201 is a global open label Phase 2b study of bomedemstat taken once daily for 24 weeks in patients with ET who are resistant to or intolerant of at least one SOC treatment NCT04254978

Bomedemstat IMG 7289 an LSD1 Inhibitor Manages the Signs and Symptoms of Essential Thrombocythemia ET While Reducing the Burden of Cells Homozygous for Driver Mutations

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